Current anti-doping analysis relies on the use of chemical techniques to detect banned substances in human supplements, and in the plasma of human and animal athletes.
Whilst analytical chemistry is effective at detecting a range of known substances, it is unable to quickly identify the emerging range of designer androgens prevalent in the sports-doping and supplement industries.
Testing of sports supplements for androgen bioactivity is of increasing importance.
A growing awareness of steroid contamination by consumers at all levels of sport has increased the need for mitigation strategies from manufacturers, including producing third-party certified products. Third-party testing often relies on known chemistry to identify individual substances.
The dietary supplement industry in the USA is a USD38.8 billion industry, with more than 85,000 supplements marketed as of 2015. The use of dietary supplements is up to 94% among elite athletes, and up to 53% of American adults.
Contact us to test your products with InsituGen’s cell-free bioassay technology.
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Detection of total androgen bioactivity in plasma can detect known and unknown androgens.
Current anti-doping analysis relies on the use of chemical techniques to detect banned substances in human supplements, and in the plasma of human and animal athletes.
Analytical chemistry techniques are effective at detecting a range of known substances using reference libraries, they are unable to quickly identify the emerging range of designer androgens prevalent in the sports-doping industry.
InsituGen’s bioassays permit detection of total androgen or estrogen bioactivity, regardless of molecular structure. Using cell-free bioassay techniques, any activation of androgenic pathways can be detected, regardless of the chemical anonymity or molecular fingerprint of the compound.
Exploiting the biological pathway using synthetic biology, InsituGen has developed bioassays capable of detecting any androgenic-activating compound, whether of known or unknown structure.
CONTACT USDetection of unknown androgens in the plasma of athletes or competing animals is possible with firstFlagX.
firstFlagX is InsituGen’s Androgen bioactivity test kit, that can allow timely out-of-competition or race-day testing to flag samples of interest, rapidly screening a larger number of competing animals per race with a low cost-per-sample.
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