Reinventing steroid hormone testing

The world’s first low-cost test for the detection of androgen and estrogen bioactivity

InsituGen’s multi-patented technology provides non-targeted detection of steroid hormone bioactivity.

Steroid hormones are important to animal and human health. Changes to the steroid hormone profile can lead to serious health conditions. There is increasing evidence that mimics of steroid hormones found in foods, supplements, and through environmental exposure may disrupt the natural steroid hormone profile and have adverse health effects. Current testing approaches will fail to capture the full steroid hormone profile in a sample.

InsituGen’s unique cell-free bioassays replicate the natural biological signalling pathways of estrogen and androgen receptors, detecting activity from any known or unknown compound that interferes with steroid hormone receptors. InsituGen’s bioassays and are simple to use, cost-effective, adaptable, fast, sensitive, and accurate.

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InsituGen offers testing of products and samples at our laboratory.

InsituGen’s cell-free bioassay technology is used for the detection of androgen and estrogen bioactivity in human supplements, products, water, and clinical research plasma samples. Our testing service is located at our New Zealand laboratory.

Learn more about the testing InsituGen offers, and the benefits it provides.

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InsituGen has developed firstFlagX®, a bioassay kit for the rapid detection of total androgenic activity.

firstFlagX® allows the detection of total androgenic activity in samples from thoroughbred racehorses, racing camels, human athletes, and their associated feed or sports supplements.

firstFlagX® is a companion to existing testing systems and workflows in analytical laboratories, allowing non-targeted, timely screening of a greater number of samples for the presence of androgens, including the hundreds of novel designer androgens that emerge every year.

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InsituGen’s bioassay technology offers the opportunity for meaningful interventions and outcomes via a wide-range of applications.

InsituGen’s unique cell-free bioassay replicates nature, detecting any activation of steroid hormone receptors.

Bioassay technology detects all bioactivity against specific receptors, without prior knowledge of chemical structures, reference libraries, or expensive specialist equipment. InsituGen’s technology is non-targeted, able to detect all bioactivity from a steroid hormone family in a sample.

The technology has been tested for a range of applications including sports doping in animals and humans, hormone profiling in companion animals, environmental water monitoring, and testing of supplements and wellness products for human use.

Learn more about InsituGen’s bioassay technology, and explore the potential applications.

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Detection of designer steroids in racing horses and camels

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Steroid hormone testing for sports and nutritional supplements and wellness products

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Wellness testing in companion animals

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Monitoring environmental steroid hormone contamination

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